Cholera Outbreak and Public Health Pharmacy in Nigeria: A Call to Action
DOI:
https://doi.org/10.51412/psnnjp.2025.45Keywords:
Cholera, Outbreaks, Public Health Pharmacy, Pharmacists, NigeriaAbstract
Public Health Pharmacy is a specialized field that focuses on the pharmacist's utilization of knowledge of diseases' patterns prevalent in neighborhoods at grassroots, amongst a wide range of Public Health activities such as key reporting and referrals up to participating in community health education programs and monitoring communicable disease patterns such as Cholera. Cholera remains a significant public health challenge in Nigeria, with frequent outbreaks causing illness and death, particularly in vulnerable communities with inadequate water, sanitation, and hygiene (WASH) infrastructure. Despite efforts by health authorities in Nigeria, the persistence of cholera outbreaks highlights gaps in disease surveillance, emergency response, and long-term preventive measures. This article explores the factors contributing to cholera outbreaks in Nigeria and underscores the roles of public health pharmacists and the urgent need for coordinated action to prevent and control Cholera, geared towards optimized and improved health for all. Addressing cholera outbreaks in Nigeria requires a multi-sectoral approach that prioritizes improved WASH infrastructure, strengthened disease surveillance, and public health education. Effective government policies, community engagement, and international support are essential to breaking the cycle of recurrent outbreaks. As Nigeria battles this public health crisis, urgent and sustained action is necessary to protect lives and build a healthier future for all.
References
1. Okafor, A (2021). A Textbook of Public Health Pharmacy. University of Lagos Press, Lagos Page 91.
2. Charles RC, Ryan ET. Cholera in the 21st century. Curr Opin Infect Dis., 2011. 24 (5), pp. 472-477. doi: 10.1097/QCO.0b013e32834a88af.
3. Snowden, FM. Emerging and reemerging diseases: a historical perspective. Immunol Rev., 2008; 225(1), pp. 9-26. doi: 10.1111/j.1600-065X.2008.00677.x
4. World Health Organization, Prevention and Control of cholera outbreaks; 2019. WHO policy and recommendations. s.l.: Accessed from: https://www.who.int/cholera/technical/prevention/control/en/.
5. United Nations International Children's Emergency Fund (UNICEF), (2019). Cholera Epidemiology and Response Factsheet Nigeria., s . l . : Accessed from : www.unicef.org/cholera/files/UNICEFFactsheet-Nigeria-EN-FINAL.pdf.
6. Anetor GO, Abraham. F. Knowledge of cholera and its prevention amongst urban residents of a district in Abuja: The pivotal role of health education.. Res J Health Sci, 2020 ; (2), pp. 102 - 112. DOI: 10.4314/rejhs.v8i2.6
7. Ajoke Olutola Adagbada, Solayide Abosede Adesida, Francisca Obiageri Nwaokorie, MaryTheresa Niemogha, Akitoye Olusegun Coker. Cholera epidemiology in Nigeria an overview.. Pan African Medical Journal, 2012; 12(1):59, pp. 1- 12. [doi: 10.11604/pamj.2012.12.59.1627]. Available online at: https://www.panafrican-medjournal.com .
8. Yamai S, Okitsu T, Shimada T, Katsube Y. Distribution of serogroups of Vibrio cholerae nonO1 non-O139 with specific reference to their ability to produce cholera toxin and addition of novel serogroups.. J Japan Assoc Infect Dis., 1994; 1 (10), pp. 1037 - 1045. doi: 10.11150/kansenshogakuzasshi1970.71.1037.
9. Kaper JB, Morris JG, Levine MM.. Cholera. Clinical Microbiology Review.,1995; 8(1), pp. 48-86. https://doi.org/10.1128/CMR.8.1.48.
10. Harris JB, Larocque RC, Charles RC, Mazumder RN, Khan AI, Bardhan PK. Cholera's western front.. Lancet., 2010;376(9757), pp. 1961-65. doi:
10.1016/S0140-6736(10)62172-1.
11. Harris JB, Larocque RC, Qadri F, Ryan ET, Calderwood SB. Cholera. Lancet, 2012; 379(9835), pp. 2466-2478. doi: 10.1016/S0140- 6736(12)60436-X.
12. Rebaudet S, Sudre B, Faucher B, Piarroux R. Cholera in coastal Africa: a systematic review of its heterogeneous environmental determinants. J Infect Dis 2013;208 Suppl 1: S98-106 DOI: 10.1093/infdis/jit202
13. Umoh JU, Adesiyun AA, Adekeye JO, Nadarajah M. Epidemiological features of an outbreak of gastroenteritis/cholera in Katsina, Northern
Nigeria.. J Hyg Camb.,1983; 91(1), pp. 101- 11. DOI: 10.1017/s0022172400060083
14. J A Ndon, S M Udo, W B Wehrenberg. Vibrioassociated gastroenteritis in the lower CrossRiver basin of Nigeria. Vibrio-associated
gastroenteritis in the lower Cross-River basin of Nigeria.. J Clin Microbiol, 1992;30(10), pp. 2730-2. doi: 10.1128/jcm.30.10.2730-2732.1992.
15. Usman, A. Sarkinfada, F. Mufunda, J. Nyarang'o, P. Mansur, K. Daiyabu, T. Recurrent Cholera Epidemics in Kano-Northern, Nigeria. Cent AfriJMed, 2005; 51 (3-4), pp. 34 - 38. https://www.panafrican-med-journal.com/content/article/12/59/full/
16. Igomu, T., n.d. Cholera epidemic: Far from being over... Cholera epid NBF News.
17. Elimian KO, M. S. M. A., Kelly Osezele Elimian, Somto Mezue, Anwar Musah, Oyeronke Oyebanji, Ibrahima Soce Fall, Sebastian Yennan,
Michel Yao, Patrick Okumu Abok, Nanpring Williams, Lynda Haj Omar, Thieno Balde, Kobina Ampah, Ifeanyi Okudo, Luka Ibrahim, Arisekola
Jinadu, Wondimagegnehu Alemu, Clement Peter & Chikwe Ihekweazu. What are the drivers of recurrent cholera transmission in Nigeria?
Evidence from a scoping review. BMC Public Health 2020; 20, 432. https://doi.org/10.1186/s12889-020-08521-y
18. Patience Ebekeyi Idoga, Mehmet Toycan, Musa Ahmed Zayyad, Analysis of Factors Contributing to the Spread of Cholera in Developing Countries. Eurasian J Med., 2019; 51(2), p. 121 – 127 . DOI: 10.5152/eurasianjmed.2019.18334
19. Ballah Akawu Denue, Cecilia Balla Akawu, Salihu Aliyu Kwayabura, Ibrahim Kida. Low case fatality during 2017 cholera outbreak in Borno
State, North Eastern Nigeria.. Ann Afr Med.,2018; 17(4), p. 2 0 3 – 2 0 9. DOI: 10.4103/aam.aam_66_17
20. World Health Organization, W. H. O. Nigeria Cholera Outbreak June 2017, s.l.: https:www.who.int/csr/don12-july-2017-
cholera-nigeria/en/.
21. Chioma Cindy Dan-Nwafor, Uzoma Ogbonna, Pamela Onyiah, Saheed Gidado, Bashorun Adebobola, Patrick Nguku, Peter Nsubuga. Cholera outbreak in a rural north central Nigerian community: an unmatched case-control study.. BMC Public Health, 2019;19(1), p. 122. DOI:
https://doi.org/10.1186/s12889-018-6299-3
22. Louise C Ivers. Advancing Control of Cholera in the Interest of the Most Vulnerable in our Global Society. J Infect Dis., 2018;218 (3), p.
S135–S136. DOI: 10.1093/infdis/jiy458
23. Martin A Mengel, Isabelle Delrieu, Leonard Heyerdahl, Bradford D Gessner. Cholera outbreaks in Africa.. Curr Top Microbiol Immunol. , 2014; 379, pp. 117 - 44. DOI: 10.1007/82_2014_369
24. Nigeria Centre for Disease Control (NCDC), (2019). An update of Cholera outbreak in Nigeria. , s . l . : https://ncdc.gov.ng/diseases/sitreps/?cat=7&name=An%20update%20of%20Cholera%20outbreak%20in%20Nigeria.
25. Benjamin L Nygren, Anna J Blackstock, Eric D Mintz. Cholera at the crossroads: the association between endemic cholera and National Access to improved water sources and sanitation.. Am J Trop Med Hyg.,2014; 91(5), pp. 1023-8. doi: 10.4269/ajtmh.14-0331.
26. Obiora CC and Kevin JD. The 2021 Cholera Outbreak in Nigeria, Data and Models Used to Explore Controls and Challenges. Commun.
Biomath. Sci., 2023;6 (2) , PP. 189-204 Available from: https://www.researchgate.net/publication/377320769_The_2021_Cholera_Outbreak_in_Nigeria_Data_and_Models_Used_to_Explore_Controls_and_Challenges. http://dx.doi.org/10.5614/cbms.2023.6.2.8
27. Nigeria Centre for Disease Control NCDC (2024) https://politicsnigeria.com/breaking-choleraoutbreak-claims-103-lives-in-nigeria-saysncdc/#google_vignette
28. Eman Merghani Ali, Moawiya Badawi Mohamed, Mosa Tawhari, Knowledge, attitude, and practice study regarding cholera among the people in Jazan city, KSA. J Family Med Prim Care; 2021; 10 (2): 712 - 7. DOI: 10.4103/jfmpc.jfmpc_965_20
29. Heather M Scobie, Christina R Phares, Kathleen A Wannemuehler, Edith Nyangoma, Eboni M Taylor, Anna Fulton, Nuttapong Wongjindanon, Naw Rody Aung, Phillipe Travers, Kashmira Date. Use of oral cholera vaccine and knowledge, attitudes, and practices regarding safe water, sanitation and hygiene in a long standing refugee camp, Thailand, 2012 2014. PLoS Negl Trop Dis. 2016; 10 (12): e0005210. DOI : 10.1371/journal.pntd.0005210
30. Mohd Rosdi, M. A. F. B., Rahman, N. A. A., & Haque, M. Knowledge, attitude, and practice regarding cholera among non academic staff of
International Islamic University Malaysia Kuantan medical campus. Bangladesh. J Med Sci, 2019; 18 (3), pp. 527 - 35. DOI:
https://doi.org/10.3329/bjms.v18i3.41621
31. Mahmood Muazu Dalhat, Aisha Nasiru Isa, Patrick Nguku, Sani-Gwarzo Nasir, Katharina Urban, Mohammed Abdulaziz, Raymond Salanga
Dankoli, Peter Nsubuga & Gabriele Poggensee. Descriptive characterization of the 2010 cholera outbreak in Nigeria.. BMC Public Health.,2014;
14, p. 1167. DOI: https://doi.org/10.1186/1471-2458-14-1167
32. Vugia DJ, Koehler JE, Ries AA. Surveillance forepidemic cholera in the Americas: an assessment.. MMWR CDC Surveill Summ.,1992:41(1), pp.
27 - 34. Accessed from https://pubmed.ncbi.nlm.nih.gov/1313536/
33. Kashmira Date, Bobbie Person, Benjamin Nygren, Vincent Were, Steve Kola, Tracy Ayers, Robert Quick. Evaluation of a rapid cholera response activity—Nyanza Province, Kenya 2008.. J Infect Dis., 2013;208(S1), pp. S62-8. DOI: 10.1093/infdis/jit369
34. Dawn L. Taylor,Tanya M. Kahawita,Sandy Cairncross, Jeroen H. J. Ensink. The impact of water, sanitation and hygiene interventions to control cholera: A systematic review.. PLoS One, 2015: 10. DOI: https://doi.org/10.1371/journal.pone.0135676
35. A Coppo, M Colombo, C Pazzani, R Bruni, K A Mohamud, K H Omar, S Mastrandrea, AM Salvia, G Rotigliano, F Maimone. Vibrio cholerae in the horn of Africa: epidemiology, plasmids, tetracycline resistance gene amplification, and comparison between O1 and non-O1 strains.. Am J Trop Med Hyg.,1995;53(4), pp. 351-9. DOI: 10.4269/ajtmh.1995.53
36. D K Olukoya, AAOgunjimi, AM Abaelu. Plasmid profiles and antimicrobial susceptibility patterns of Vibrio cholerae O1 strain isolated during a recent outbreak in Nigeria.. Journal of Diarrhoeal Diseases Res. 1995; 13(2):118-21. , 13(2), pp. 118 - 121. Accessed from https://pubmed.ncbi.nlm.nih.gov/7594312/
37. Karin Gallandat, Annie Huang, Justine Rayner, Gabrielle String, Daniele S Lantagne. Household spraying in cholera outbreaks: Insights from three exploratory, mixed methods field effectiveness evaluations. . PLOS NeglTropDis. 2020; 14 (8): e0008661. doi: 10.1371/journal.pntd.0008661.
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