Application Of Melon Seed Oil In Methyl Salicylate Liniment And Salicylic Acid Lotion Formulations

Abstract

Melon seed oil was obtained by soxhlet extraction using petroleum ether (40 - 60°C). The oil was processed by filtration, dewaxing, degumrnirtg, refining, bleaching and winterization. The physico-chemical properties of the oil and the constituent fatty acids were determined. The melon oil was used to formulate batches of methyl salicylate liniment and salicylic acid lotion respectively.The products obtained were compared with similar B. P. C. formulations of these drugs where arachis oil was the oily component used. The liniment and lotion formulations containing melon oil performed better than those containing arachis oil in terms of the amount of the drugs remaining at determined time intervals after storage.