Effect Of Binder And Disintegrant Concentration On The Dissolution Rate Of Medicaments From Tablet Formulations.

Authors

  • J. S. M. Garr Department of Pharmaceutics and Pharmaceutical Microbiology Faculty of Pharmaceutical Sciences
  • A. B. Bangudu Department of Pharmaceutics and Pharmaceutical Microbiology Faculty of Pharmaceutical Sciences,

Abstract

The separate effects of varying the concentrations of sorghum and maize starch when used as tablet binder and a disintegrant on the dissolution rate of acetylslicylic acid tablets have been investigated. The dissolution rate of tablets decreased with increasing binder concentration and a direct correlation was observed betweendisintegrant concentration and dissolution rate. Acetylsalicylic acid tablets formulated from sorghum starch had shorter disintegration times and higher dissolution rates than those formulated from maize starch under the same experimental conditions.

(Preview the download for more on the abstract.)

Downloads

Published

1992-12-01

How to Cite

Garr, J. S. M., & Bangudu, A. B. (1992). Effect Of Binder And Disintegrant Concentration On The Dissolution Rate Of Medicaments From Tablet Formulations. The Nigerian Journal of Pharmacy, 23(3). Retrieved from https://psnnjp.org/index.php/home/article/view/268

Issue

Vol. 23 No. 3 (1992): Nigerian Journal of Pharmacy

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.