Effect Of Levamisole On Plasma Creatinine And Cholesterol Levels And Plasma Alkaline Phosphatase And Liver Microsomal Drug Metabolising Enzymes Activities In Male Rats.

Authors

  • G.K. Isanah Department of Pharmaceutical Chemistry, College of Medicine, University of Lagos
  • H.A.B. Coker Department of Pharmaceutical Chemistry, College of Medicine, University of Lagos, Nigeria
  • M. M. Mohammed Nigerian Institute of Medical Research, Yaba, Lagos
  • J.K. Renner Department of Paediatrics, College of Medicine, University of Lagos
  • F. Tayo Departrnent of Clinical Pharmacy & Biopharmacy, College of Medicine, University of Lagos
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Abstract

Adult male albino rats were injected inlnt-peritoneally once daily for 14 consecutive days with 20mgkg- 1 dose of levamisole dissolved in distilled water. The control received equivalent volumes of distilled water only. Levamisole modestly increased the activities of all the micromisole  drug metabolizing enymes detemiined which include NADPH -Cytochrome Credutase, Cytochromeb5 and Aniline hydroxylase.

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Published

1993-09-01

How to Cite

Isanah, G., Coker, H., Mohammed, M. M., Renner, . J., & Tayo, F. (1993). Effect Of Levamisole On Plasma Creatinine And Cholesterol Levels And Plasma Alkaline Phosphatase And Liver Microsomal Drug Metabolising Enzymes Activities In Male Rats. The Nigerian Journal of Pharmacy, 24(3). Retrieved from https://psnnjp.org/index.php/home/article/view/272

Issue

Vol. 24 No. 3 (1993): Nigerian Journal of Pharmacy

Section

Research Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.