Chloroquine-Chlorpheniramine Interaction In Human Malaria

Authors

  • C.A. Okonkwo Biochemistry Division, Nigerian Institute of Medical Resaerch, Yaba, Lagos, Nigeria.
  • H.A.B. Coker School of Pharmacy, College of Medicine of the University of Lagos, Nigeria.
  • P. U. Agomo Biochemistry Division, Nigerian Institute of Medical Resaerch, Yaba, Lagos, Nigeria.
  • C. O. Agomo Biochemistry Division, Nigerian Institute of Medical Resaerch, Yaba, Lagos, Nigeria.
  • R. Anyanwu Emzor Pharmaceutical Industries, Lagos, Nigeria.
  • V. N. Asianya Biochemistry Division, Nigerian Institute of Medical Resaerch, Yaba, Lagos, Nigeria.
  • S. K. Akindele Biochemistry Division, Nigerian Institute of Medical Resaerch, Yaba, Lagos, Nigeria.

Abstract

The purpose to this study was to examine the etlect at chloroquine- chlorpheniramine (CG-CF) combination therapy on the efficacy and disposition ot chloroquine (CQ) in acute uncomplicated malaria. A 3- day standard treatment with 25mg CQ base per kilogram body weight alone or in combination with chlorpheniramine (CP) was orally administered to 17semi-immune Nigerian children with Plasmodium falciparum parasitemia, attending the Massey Street Children's Hospital , Lagos, Nigeria.

 

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Published

2000-01-01

How to Cite

Okonkwo, C. ., Coker, H. ., Agomo, P. U. ., Agomo, C. O. ., Anyanwu, R. ., Asianya, V. N. ., & Akindele, S. K. . (2000). Chloroquine-Chlorpheniramine Interaction In Human Malaria. The Nigerian Journal of Pharmacy, 31(1). Retrieved from https://psnnjp.org/index.php/home/article/view/253

Issue

Vol. 31 No. 1 (2000): Nigerian Journal of Pharmacy

Section

Articles

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.