Topochemical Photoreactions In Drug Products And Drug Preparations

Abstract

Under the action of light, drug products may be transformed into different products according to whether they are in solution or in a crystalline form. In topochemical reactions the product is dependent upon the conformation immobilized in the crystall lattice, as well as, occasionally, on the suvounding atmosphere. In order to exclude any solvent effects, the light stability testing of solid drug
preparations or crystalline drug substances has to be carried out on solid samples. Suitable testing methods will be considered.

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