Effect Of Surfactants On Some Physical Properties Of Paracetamol Tablets.

Authors

  • M. A. lwuogwu Department of Pharmaceutics and Phamarceutical Technology, Faculty of Pharmacy, University Of Benin, Benin City, Nigeria
  • A. O. Onyekweli Department of Pharmaceutics and Phamarceutical Technology, Faculty of Pharmacy, University Of Benin, Benin City, Nigeria
  • E. Osogie Department of Pharmaceutics and Phamarceutical Technology, Faculty of Pharmacy, University Of Benin, Benin City, Nigeria

Abstract

The effect of surfactants added to paracetamol  (acetaminophen) granulations as well as the effect of the method at incorporating the surtactants on some physicochemical characteristics of the tablets have been investigated. Results obtained indicate that Tween ® 80 treated granulation gave tablets with superior dissolution profile in comparison with tablets compressed tram sodium lauryl sulphate treated granulation. This was inspite of the tormer having a longer disintegration time than the latter.

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Published

2002-04-01

How to Cite

lwuogwu, M. A., Onyekweli , A. O., & Osogie , E. (2002). Effect Of Surfactants On Some Physical Properties Of Paracetamol Tablets. The Nigerian Journal of Pharmacy, 33(1). Retrieved from https://psnnjp.org/index.php/home/article/view/246

Issue

Vol. 33 No. 1 (2002): Nigerian Journal of Pharmacy

Section

Articles

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.