Pattern of drug utilisation, medication adherence, and treatment satisfaction among diabetic patients in a secondary hospital in southern Nigeria


  • Unyime Israel Eshiet Department of Clinical Pharmacy & Biopharmacy,
  • Abasiodiong Uwak Department of Clinical Pharmacy & Biopharmacy,
  • Blessing Ante Department of Clinical Pharmacy & Biopharmacy


Antidiabetic Drugs, Medication Adherence, Treatment Satisfaction


Background: Drug use evaluations provide insights into the effiffifficiency of drug use and may promote rational use of drugs, medication adherence and patient satisfaction with treatment. This study seeks to determine the current pattern of utilization of antidiabetic drugs, patient's adherence, and satisfaction with treatment among diabetic patients in a secondary hospital in southern Nigeria.

Methods: A cross sectional prospective antidiabetic drug utilization study was conducted among patients with diabetes mellitus receiving care at General Hospital, Ikot Ekpene between November 2019 and February 2020. Data on antidiabetic drug use pattern was obtained via an assessment of patients' prescriptions. Patients' medication adherence and satisfaction with treatment offffered was assessed using the 4-Item Morisky Medication-Taking Adherence Scale and the Treatment Satisfaction Questionnaire for Medication (Version 1.4). Descriptive statistics was used to summarize data, inferential statistics was used where applicable with statistical signifificance set at p<0.05.

Results: The Sulphonylureas were the most frequently prescribed class of antidiabetic drugs (69.2%). A combination of antidiabetic agents was prescribed in 80.8% of the patients. Clinically signifificant and potentially dangerous drug-drug interactions was identifified in 91.7% of the prescriptions. The mean global satisfaction with treatment scores of the patients was 61.4(±8.3). The mean medication adherence scores of the patients was 2.1(±1.2). There was a statistically signifificant relationship between patients' global satisfaction with treatment score and the medication adherence score (r = 0.350; p = 0.0001).

Conclusion: Sulphonylureas were the most frequently used class of antidiabetic agents in this population. Patients were generally satisfified the treatment offffered. However, the level of adherence to prescribed antidiabetic drugs was poor. There is a compelling need for greater involvement of pharmacists in the provision of clinical services for patients with diabetes mellitus.

Author Biographies

Unyime Israel Eshiet, Department of Clinical Pharmacy & Biopharmacy,

University of Uyo, Nige

Abasiodiong Uwak, Department of Clinical Pharmacy & Biopharmacy,

University of Uyo, Nigeria.

Blessing Ante, Department of Clinical Pharmacy & Biopharmacy

 University of Uyo, Nigeria


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How to Cite

Israel Eshiet, U. ., Uwak, A. ., & Ante, B. . (2021). Pattern of drug utilisation, medication adherence, and treatment satisfaction among diabetic patients in a secondary hospital in southern Nigeria. The Nigerian Journal of Pharmacy, 55(2), 24–34 | Retrieved from