Effect of some Drugs on Bioavailability of Oxytetracycline Hydrochloride in Rabbits
Abstract
Biological availability of Oxytetracycline hydrochloride was significantly decreased in presence of paramethasone acetate, Acetyl barbromal, Hydroxyzine Hydrochloride, cephalothin Sodium, Clindomycin hydrochloride, mefen- amic acid and Iron. Whereas meprednisone caused only slight decrease, while Ascorbic acid, tartaric acid. Tybamate, and Triamcinclone diacetate were not found to affect the bio-availability of oxytetracycline in experimental animals.
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