Knowledge and attitudes of health workers regarding adverse drug reactions monitoring and reporting in HIV treatment centers in Nigeria

Abstract

Background:

Adverse drug reaction (ADP!) monitoring and reporting is pivotal to the withdrawal of several  approved and licensed drugs from the market because of drugs induced toxicities. However, under-reporting is a major problem and the underlying factors may vary between countries. The study evaluated knowledge and attitudes of health workers regarding adverse drug reactions (ADR) monitoringand reportingin Nigeria.

Methods:

This was a cross-sectional study. Out of 7126 health workers (doctors, pharmacists, nurses and laboratory scientists) in 51 secondary hospitals, a study-specific questionnaire was administered to 1160 participants who were selected using stratified random sampling technique. A midpoint of the 5- pomt Likert-type attitude scale was determined by adding all scores and computing the average. Mean scale scores above midpoint were regarded as positive attitudes while below as negative attitudes. Chi-square was used for inferentiai statistics and P<0.05 indicated statistical significance.

Results:

The mean questionnaire return rate was 60.1%. Data from 728(62.8%) participants were analyzed; and included 148{20.3%) doctors, 139(19.1%) pharmacists, 349(47.9%) nurses and 85{11.?%l laboratory scientists. Majority of the participants (35.6%) had >15years...

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