Developing Novel Drug Delivery Systems for Antibiotic-Sensitive SARS-Cov-2

Authors

  • Simisola Oloye
  • Sunday Ndiana-Abasi Centre for Nanomedicine and Biophysical Drug Delivery,
  • Oluwafunke Obembe Centre for Nanomedicine and Biophysical Drug Delivery,
  • Marlene Ekpo School of International Education,

Abstract

Oral formulations are the most convenient and preferred route of delivering drugs into the systemic circulation. However, the challenge of short gastric retention time is what floating drug delivery system (FDDS) seeks to address. Floating drug delivery systems are oral dosage forms that increase the gastric retention time of drugs and help achieve more effective control of fluctuations in plasma drug concentrations of oral formulations. Polymers are usually employed in designing floating drug delivery systems as they help target the drug's delivery Both synthetic and natural polymers can be used in floating drug delivery systems. Natural polymers are preferable due to their proven biocampatibility and safety. They are non-toxic, safe, possess gel-forming property, capable of undergoing chemical modification and less expensive

Author Biographies

Simisola Oloye

1. Centre for Nanomedicine and Biophysical DRug Delivery, National Institute for Pharmaceutical Research and Development (NIPRD) in Nigeria.

2. Department of Pharmaceutical Technology and raw materials Development, national Institute for Pharmaceutical Research and Development (NIPRD) in Nigeria

Sunday Ndiana-Abasi, Centre for Nanomedicine and Biophysical Drug Delivery,

National Institute for Pharmaceutical Research and Development (NIPRD) in Nigeria.

Oluwafunke Obembe, Centre for Nanomedicine and Biophysical Drug Delivery,

National Institute for Pharmaceutical Research and Development (NIPRD) in Nigeria.

Marlene Ekpo, School of International Education,

Southern Medical University , Guangzhou, Guangdong, China

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Published

2017-03-28